Rejuran Salmon DNA

Polynucleotide skin-quality treatment

Rejuran aims to support the skin's natural renewal and repair processes using polynucleotide (PN) technology. It is an approach that focuses on improving skin quality without changing your skin; unlike filler, it does not aim to create volume or change facial contours.

Active substance: Purified polynucleotides (PN) of salmon origin
Procedure time: About 20–30 minutes
Onset of effect: In the weeks after the first sessions
Longevity: Varies with the session plan and the skin

What is it?

Rejuran is an injectable skin-quality treatment containing purified polynucleotides (PN) of salmon origin. It is known as the original Asia-Pacific salmon DNA treatment.

Rather than giving the skin only surface hydration, it focuses on supporting the skin's own renewal mechanisms. By supporting collagen and elastin production, the aim is an improvement in skin texture, elasticity and overall skin appearance over time.

In short: filler is for volume and contour; Rejuran is for skin quality and renewal support. The aim is skin quality that looks healthier, stronger, smoother and more rested.

Dr. Burak Demirhan Explains

Is all salmon DNA the same? (in Turkish)

English translation of the answer

Is all salmon DNA the same? Why is Asia-Pacific salmon so special? The answer is actually very clear: no, not all salmon DNA is the same. Asia-Pacific salmon is one of the most resilient creatures in nature. The secret of this extraordinary resilience lies in the length, purity and stability of its DNA chain. When used in the skin, these long polynucleotide chains practically tell the cells: start working again. Cellular renewal becomes active, and elasticity and hydration balance are regained. In short, DNA from one of nature's strongest creatures helps the skin regain its strength too.

Is it suitable for every skin type? (in Turkish)

English translation of the answer

Is the Asia-Pacific salmon DNA treatment suitable for every skin type? Absolutely, yes. Asia-Pacific salmon DNA shows roughly 97% biological compatibility with human DNA. This similarity allows us to achieve compatible and balanced results across very different skin types. It can be applied comfortably even to atopic, acne-prone or sensitive skin. We are talking about a structure of biological origin that contains no toxic components. In other words, the skin receives support to renew itself in the form closest to its own nature.

What Is Rejuran Used For?

Rejuran may be chosen particularly for skin that is dull, tired, beginning to lose elasticity or showing fine signs of ageing. Rather than changing your face, it aims to make your skin look better.

Supporting skin quality
Reducing the appearance of fine wrinkles
Supporting skin elasticity
A smoother skin texture
A livelier, more rested appearance
Supporting the skin's natural repair processes

Animated Explainer

What does salmon DNA (polynucleotide) do for the skin? (in Turkish)

English translation of the on-screen text

A new-generation skin healer. Made from DNA fragments obtained from wild salmon; it activates the skin's own ability to renew itself. From wild salmon: a reliable medical device. Salmon DNA is produced from purified polynucleotides (PN). Breaks down slowly in the tissue: it breaks down slowly within the tissue while keeping its regular structure. Dermis and epidermis: renews their biological structure. It increases skin elasticity by renewing the biological structure of the dermis and epidermis. Skin elasticity and fine wrinkles: supports collagen production. It repairs thin skin damaged from within by ageing and reduces the appearance of wrinkles. Skin tone and texture: a natural glow. It improves pigmentation and the overall brightness of skin tone; it helps give the skin a smoother texture. Highly biocompatible: high compatibility with human DNA. It consists of DNA fragments with high biocompatibility. Targeted treatment area: skin repair for the whole face, wrinkles around the eyes and acne scars. Who is this treatment suitable for? People who want naturally healthy skin, who aim to refresh and firm their face, who have fine facial wrinkles, and who have sensitive, thin skin. Natural skin beauty: elasticity and hydration. It strongly increases skin elasticity and hydration, revealing the skin's natural beauty. Dr. Burak Demirhan, Küçükyalı, Istanbul. Animations are illustrative. Suitability and results vary from person to person; the decision is made at the physician's examination.

Treatment Areas

Face — overall skin quality
Around the eyes — a separate form for thin-skinned areas
Neck and décolletage
Back of the hands

Procedure Steps

Assessment
Rather than applying a standard protocol to everyone, skin quality, signs of ageing, the treatment area and your expectations are assessed first. The aim is not to do more procedures but to apply the right protocol, to the right patient, in the right area. Asking about allergy to fish-derived products is especially important for this treatment.
Preparation
The area is cleaned with antiseptic; a topical anaesthetic cream is applied if you wish.
Treatment
The form suited to the area is delivered into the skin as micro-injections. A session takes about 20–30 minutes.
Session plan and follow-up
It may not be limited to a single session; the number of sessions and the intervals are set at the consultation according to the condition of the skin. There is a check between sessions, and the plan is reviewed together.

Duration and Longevity

The effect comes not from the product itself being permanent but from supporting the skin's own repair process. For this reason the duration varies with the person's skin structure, age and lifestyle habits; no fixed duration is given in advance. Once the sessions are complete, a repeat plan is discussed at the consultation if needed.

Who is it suitable for?

People whose skin looks dull and tired
People whose fine wrinkles are starting to become noticeable
People who feel a loss of elasticity
People who want their skin texture to look smoother
People aiming for a healthier appearance without adding volume to the face

Who is it not suitable for?

Pregnant and breastfeeding people
People with an active infection, a herpes outbreak or an open wound in the treatment area
People with a bleeding disorder, and people taking blood thinners without the physician's approval
People with an uncontrolled autoimmune disease
Under 18s
People with a known allergy to fish-derived products
People expecting an immediate change in volume — this product is not a filler

Aftercare

For the first 24 hours, do not massage the area or apply make-up.
Avoid saunas, Turkish baths and strenuous exercise in the first days.
Using sunscreen is recommended.
The small bumps at the injection points usually settle within a short time; do not interfere with them.

Possible Side Effects

Temporary redness and raised bumps at the injection points
Temporary swelling and tenderness
Bruising — more likely around the eyes in particular
Rarely, infection
Rarely, an allergic reaction; a history of fish allergy is asked about at the consultation

Frequently Asked Questions

Is Rejuran a filler?

No. Rejuran is not a classic hyaluronic acid filler. It is not used to add volume to facial contours, enlarge the lips or change the contour of the face. Nor is it a treatment aimed at reducing muscle movement. It is one of the options that can be considered by people who want to invest in skin quality while keeping their natural appearance.

Are Rejuran and salmon DNA the same thing?

"Salmon DNA" is the everyday name for the treatment; Rejuran is one of the products in this group. One is the name of the method, the other the name of the product.

How many sessions are needed?

It is not a single-session treatment. The number of sessions and the intervals are set at the consultation according to the condition of the skin; the same number is not applied to everyone.

When does the result become visible?

It is not a procedure that gives an immediate result. The first change is usually noticed in the weeks after the first sessions; the result continues to become clearer over the following weeks.

Can it be used around the eyes?

More fluid forms exist for the area around the eyes, and this area is one of those where the treatment is often chosen. Because the skin there is thin, bruising is more likely; suitability is assessed separately.

How is the treatment planned?

Rather than applying a standard protocol to everyone, skin quality, signs of ageing, the treatment area and your expectations are assessed first. The aim is not to do more procedures but to apply the right protocol, to the right patient, in the right area. Whether Rejuran is suitable for you, and your individual session plan, are decided at the consultation.

Is it spelled Rejuran or rejüran?

The correct spelling of the product is Rejuran. In searches, different spellings such as rejüran, rejüren and recüran are often used; they all refer to the same product.

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